Virus Quiz (UPSC Prelims Level)
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1. With reference to viruses, which of the following statements is/are correct?
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Correct answer: B – 1 and 3 only. All viruses are obligate intracellular parasites, but an individual virus has either DNA or RNA, not both. Some can be crystallized outside the host.
2. Consider the following statements regarding RNA viruses:
Which of the statements given above is/are correct?
Correct answer: B – 1 and 3 only. RNA viruses mutate faster due to error-prone polymerases and some (+) sense RNA viruses act directly as mRNA. Not all RNA viruses are enveloped.
3. Which of the following best describes a retrovirus?
Correct answer: B – Retroviruses (such as HIV) are RNA viruses that use the enzyme reverse transcriptase to synthesize DNA from RNA inside host cells.
4. With reference to bacteriophages, which of the following statements is/are correct?
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Correct answer: A – 1 and 2 only. Bacteriophages can follow lytic or lysogenic cycles and are important tools in genetics. They can transfer bacterial genes by transduction, so statement 3 is incorrect.
5. Which of the following best explains why antibiotics are generally ineffective against viral infections?
Correct answer: A – Antibiotics act on bacterial cell wall synthesis, protein synthesis and other metabolic pathways, which viruses lack because they rely on the host cell machinery.
6. In the context of public health, “herd immunity” against a viral disease depends primarily on which of the following?
Which of the statements given above is/are correct?
Correct answer: B – 1 and 2 only. Herd immunity depends on how many people are immune and the R₀ of the virus. Environmental survival influences transmission but is not a direct parameter in herd immunity thresholds.
7. Consider the following pairs:
Virus – Primary mode of transmission
Which of the pairs given above is/are correctly matched?
Correct answer: A – 1 and 3 only. Hepatitis B spreads mainly via blood/body fluids; influenza via respiratory droplets. Rabies is transmitted chiefly by bites (saliva), and HPV is primarily sexually transmitted, not vector-borne.
8. With reference to viral vaccines, which of the following statements is/are correct?
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Correct answer: B – 1 and 2 only. Live attenuated vaccines mimic natural infection and often give stronger immunity; inactivated vaccines are usually safer in immunocompromised hosts. Not all vaccines provide sterilizing immunity.
9. In the context of viral replication, what does the “latent period” refer to?
Correct answer: B – In virology, the latent period is the time between entry of the virus into a cell and the first release of new virions, distinct from the incubation period of disease.
10. Which of the following characteristics can help distinguish viruses from prions?
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Correct answer: B – 1 and 2 only. Viruses have nucleic acids and can be affected by nucleic acid–degrading agents. Prions are misfolded proteins without nucleic acid (statement 3 describes prions, not viruses).
